Structure of PDB 7xjg Chain A Binding Site BS03

Receptor Information
>7xjg Chain A (length=314) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAEYLNTFRLRNLGLPVMNNLHDMSKATRISVETLRLLIYTADFRYRIYT
VEKKGPEKRMRTIYQPSRELKALQGWVLRNILDKLSSSPFSIGFEKHQSI
LNNATPHIGANFILNIDLEDFFPSLTANKVFGVFHSLGYNRLISSVLTKI
CCYKNLLPQGAPSSPKLANLICSKLDYRIQGYAGSRGLIYTRYADDLTLS
AQSMKKVVKARDFLFSIIPSEGLVINSKKTCISGPRSQRKVTGLVISQEK
VGIGREKYKEIRAKIHHIFCGKSSEIEHVRGWLSFILSVDSKSHRRLITY
ISKLEKKYGKNPLN
Ligand information
Receptor-Ligand Complex Structure
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PDB7xjg Cryo-EM structures of Escherichia coli Ec86 retron complexes reveal architecture and defence mechanism.
Resolution2.51 Å
Binding residue
(original residue number in PDB)		Y6 L7 F10 R13
Binding residue
(residue number reindexed from 1)		Y4 L5 F8 R11
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003964 RNA-directed DNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006278 RNA-templated DNA biosynthetic process
GO:0006974 DNA damage response
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7xjg, PDBe:7xjg, PDBj:7xjg
PDBsum7xjg
PubMed35982312
UniProtP23070|RT86_ECOLX Retron Ec86 reverse transcriptase (Gene Name=ret)

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