Structure of PDB 7xga Chain A Binding Site BS03

Receptor Information
>7xga Chain A (length=126) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPLGSGPSCRFCKDDENKPCRKCACHVCGGREAPEKQLLCDECDMAFHLY
CLKPPLTSVPPEPEWYCPSCRTDSRREVQSAFPKRRVRTLLSVLKDPIAK
MRRLVRIEQRQKRLEGNEFERDSEPF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7xga Chain A Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7xga Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger.
ResolutionN/A
Binding residue
(original residue number in PDB)		C25 C28 H48 C51
Binding residue
(residue number reindexed from 1)		C25 C28 H48 C51
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0035064 methylated histone binding

View graph for
Molecular Function
External links
PDB RCSB:7xga, PDBe:7xga, PDBj:7xga
PDBsum7xga
PubMed36420895
UniProtQ8QZY3;
Q8VDF2|UHRF1_MOUSE E3 ubiquitin-protein ligase UHRF1 (Gene Name=Uhrf1)

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