Structure of PDB 7xfg Chain A Binding Site BS03

Receptor Information
>7xfg Chain A (length=102) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGGRATQSPGDSRRLSIQRAIQSLVHAAQCRNANCSLPSCQKMKRVVQHT
KGCKRKTNGGCPICKQLIALAAYHAKHCQENKCPVPFCLNIKQKGSEFPA
GN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7xfg Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7xfg Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation
ResolutionN/A
Binding residue
(original residue number in PDB)		H26 C30 C35 C40
Binding residue
(residue number reindexed from 1)		H26 C30 C35 C40
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7xfg, PDBe:7xfg, PDBj:7xfg
PDBsum7xfg
PubMed
UniProtQ09472|EP300_HUMAN Histone acetyltransferase p300 (Gene Name=EP300)

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