Structure of PDB 7xeb Chain A Binding Site BS03

Receptor Information
>7xeb Chain A (length=533) Species: 673 (Grimontia hollisae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EQCDLSQFQTTSSNQLMAAIRQQGASCVNALFSADTGVQEAAFSSNHMYN
VAQYTRTLAQQYAGGGSDELEALYLYLRAGYYAEFYNSNITFLSWVTPAV
KGAVDAFVQNAHFYDNGDAHGKVLNEVIITMDSAGLQHAYLDVVTQWLTR
WNAQYAEHWYMRNAVNGVFTLLFGGQWNNQYTSLIGEQTALVTALQAFAL
DRTKVNSPTEFMAANAARELGRLARYTDATIAPKVTEGLTAIFGQYPSYG
DGDAIWLGAADTASYYADCSQFNICGFEDALRDAALNQTFICSDTIKIRS
QDMSQAQHLAACDKMAYEESFFHTTLETGNQPVADDHNTQLQVNIFNSDT
DYGKYAGPIFGIDTNNGGMYLEGNPANVGNIPNFIAYEASYANPDHFVWN
LEHEYVHYLDGRFNMYGDFGTPTELVVWWSEGVAEYVSRVNDNPQAIATI
QDGSTYTLAQVFDTTYDGFDVDRIYRWGYLAVRFMFERHPDEVQRMLSAT
RQGRWAEYKAIISGWANQYQSEFAQWTEALAKG
Ligand information
Receptor-Ligand Complex Structure
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PDB7xeb Crystal structure of Grimontia hollisae collagenase provides insights into its novel substrate specificity toward collagen.
Resolution2.39 Å
Binding residue
(original residue number in PDB)		F121 R167 Y171 F174 E215 D221
Binding residue
(residue number reindexed from 1)		F32 R78 Y82 F85 E126 D132
Enzymatic activity
Enzyme Commision number 3.4.24.3: microbial collagenase.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xeb, PDBe:7xeb, PDBj:7xeb
PDBsum7xeb
PubMed35679897
UniProtF7IZI6

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