Structure of PDB 7w79 Chain A Binding Site BS03

Receptor Information
>7w79 Chain A (length=216) Species: 257309 (Corynebacterium diphtheriae NCTC 13129) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAPVLSITNASVVYPDGISTVTALDSANVEIFPGELVAIVGESGSGKSTL
LSIAGFLQEPTSGTVTLHGAEGLDATSTRREHIGFVFQQPNLLGSLTARE
QLLITDHLRGIKPRKDRADELLARVGLKGLGGRRVAQLSGGQRQRVNIAR
ALMGNPQLLLADEPTSALDARLSKEIVELLRDVTKEFALATLMVTHDRSQ
LAYADRFVEMADGKAL
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7w79 Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7w79 Structural basis for heme detoxification by an ATP-binding cassette-type efflux pump in gram-positive pathogenic bacteria.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		S50 Q90
Binding residue
(residue number reindexed from 1)		S48 Q88
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0022857 transmembrane transporter activity
GO:0046872 metal ion binding
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7w79, PDBe:7w79, PDBj:7w79
PDBsum7w79
PubMed35767641
UniProtQ6NEF2

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