Structure of PDB 7vdv Chain A Binding Site BS03

Receptor Information
>7vdv Chain A (length=809) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVDPVEILQEREYR
LQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVC
MRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQ
EYLNSILQHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKKLIDQK
KDKRLAYLLQQTYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSL
YNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNW
AYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKH
ILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKL
PELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRL
HKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLL
TDGSGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLY
RASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRL
DGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDS
DWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQ
KVIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVPDDETVNQMIARH
EEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKEKMFGRGSRH
RKEVDYSDS
Ligand information
Ligand IDBEF
InChIInChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
InChIKeyOGIAHMCCNXDTIE-UHFFFAOYSA-K
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[Be-](F)(F)F
ACDLabs 10.04
CACTVS 3.341		F[Be-](F)F
FormulaBe F3
NameBERYLLIUM TRIFLUORIDE ION
ChEMBL
DrugBank
ZINC
PDB chain7vdv Chain A Residue 1701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7vdv Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		M781 K785 R1189 R1192
Binding residue
(residue number reindexed from 1)		M263 K267 R663 R666
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0042393 histone binding
GO:0140658 ATP-dependent chromatin remodeler activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7vdv, PDBe:7vdv, PDBj:7vdv
PDBsum7vdv
PubMed35477757
UniProtP51532|SMCA4_HUMAN Transcription activator BRG1 (Gene Name=SMARCA4)

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