Structure of PDB 7uwv Chain A Binding Site BS03

Receptor Information

>7uwv Chain A (length=531) Species: 657321 (Ruminococcus bromii L2-63)

HAYGYTLTANNTAFSTESLDVKLALKNADKGYYSVDGSAKKEFANGDSVK
VGEGKIGNSKVTLTLYATGADGVETEQTYTFKKTFTASKTTFSAKSDGHT
TAPESGYYGTNPEMQLGKHKTISVDGDLSDWDSSMIIAQGVANDDPRVYM
PSSMHEQPWDAYALYSAWDDDNLYFLLEMANTTYITSPEDNFAASNEARP
WRNSIPMYLALSIDPAKQATGKAVGTNKDGSVYTNPFVWGCTNGTAKDGG
TGFTTHIDTLVAFDSNNSNGGASIFKADTQDTDGTYMFNYDTRIPIGVTS
FQAQDNKNGFKIKYANGTKSTSIFGINAPKGSRVMGDNLDMNSNWVDFFD
EGYKNSYGYVYEIAVPLNTLGIDRSYIETQGIGAMQILTYGTSGMDTLPH
DPSMLDQANLEYSYDPSTSHEKEDIDNITVPLARIGALLPDTEVNEAPFE
VNFGANLNSGQSAGTPITLLAESYHATGDVTYSFTVNGETVQNSNTDSCV
WTPSADGTYSIGVVAVDANGNKAESTKTFVV

Ligand information

• Ligand ID: GLC
• InChI: InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
• InChIKey: WQZGKKKJIJFFOK-DVKNGEFBSA-N
• SMILES:
  OpenEye OEToolkits 1.5.0: C(C1C(C(C(C(O1)O)O)O)O)O
  OpenEye OEToolkits 1.5.0: C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
  CACTVS 3.341: OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
  CACTVS 3.341: OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
  ACDLabs 10.04: OC1C(O)C(OC(O)C1O)CO
• Formula: C6 H12 O6
• Name: alpha-D-glucopyranose;
  alpha-D-glucose;
  D-glucose;
  glucose
• ChEMBL: CHEMBL423707
• ZINC: ZINC000003861213
• PDB chain: 7uwv Chain L Residue 6

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7uwv The structure of starch-binding protein Sas6 from Ruminococcus bromii reveals that CBM74 and CBM26 cooperate to bind resistant starch
• Resolution: 1.7 Å
• Binding residue (original residue number in PDB): Y546 Y548
• Binding residue (residue number reindexed from 1): Y412 Y414
• Annotation score: 4

External links

• PDB: RCSB:7uwv, PDBe:7uwv, PDBj:7uwv
• PDBsum: 7uwv
• PubMed: 38177679
• UniProt: A0A2N0UYM2