Structure of PDB 7uux Chain A Binding Site BS03
Receptor Information
>7uux Chain A (length=353) Species:
10090
(Mus musculus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTG
SYYEHVKISAPNQFNVMFKLEVPRIELQEYYETGAFYLVKFNPLSHFLEG
EVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEI
SVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKD
GNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYL
LEQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLA
FFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIF
DKL
Ligand information
>7uux Chain I (length=18) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
atctgtacatgtacagat
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7uux
ATP binds to Cyclic GMP AMP synthase (cGAS) through Mg coordination
Resolution
2.26 Å
Binding residue
(original residue number in PDB)
K335 T338
Binding residue
(residue number reindexed from 1)
K181 T184
Enzymatic activity
Enzyme Commision number
2.7.7.86
: cyclic GMP-AMP synthase.
External links
PDB
RCSB:7uux
,
PDBe:7uux
,
PDBj:7uux
PDBsum
7uux
PubMed
UniProt
Q8C6L5
|CGAS_MOUSE Cyclic GMP-AMP synthase (Gene Name=Cgas)
[
Back to BioLiP
]
