Structure of PDB 7u1y Chain A Binding Site BS03

Receptor Information
>7u1y Chain A (length=439) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMKFLNPPFPYSMTSDPESFGHECFTRRWGIILTGIEKDVSERLSKLAST
SKDSEVVAQGKPLLNDLEAFKSDIKNDRPLVPLEGEGQDIVEYNEELKQL
DNASWGNAPWLYSECYYYRRISLIFARYSEWKAYDPFFQQKDSTLKSSRA
AVEELAGRYCLLEEELNSIAKKGDSHIAYMVFVEMAQISLWGNATDLSLL
TNLSYEELQNLQGQKVVEESQKNILVNDFPTVWSKLKDVHNGRIDFVLDN
AGFELYVDLIFAAYLLKAGIAKEIVLHPKDFPWFVSDVLPYDIEYLLTNL
DTIFPTESVTKFATDLRSFSAKGQLRLRTDPFWTTAHYFGRMPDFAAGLL
TELEKSDMIFFKGDLNYRKLTGDCLWPRTTPFGKTLGPIANAINACALRT
CKADVVVGLPDGLYEKIAKDLPHWERTGKYAVVEFCPKA
Ligand information
Ligand IDALF
InChIInChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
InChIKeyUYOMQIYKOOHAMK-UHFFFAOYSA-J
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al-](F)(F)F
FormulaAl F4
NameTETRAFLUOROALUMINATE ION
ChEMBL
DrugBankDB04444
ZINC
PDB chain7u1y Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7u1y Fission yeast Duf89 and Duf8901 are cobalt/nickel-dependent phosphatase-pyrophosphatases that act via a covalent aspartyl-phosphate intermediate.
Resolution1.81 Å
Binding residue
(original residue number in PDB)		N192 D195 D248 N249 G362 D363 L364 K401
Binding residue
(residue number reindexed from 1)		N193 D196 D249 N250 G363 D364 L365 K402
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.-
Gene Ontology
Molecular Function
GO:0004427 inorganic diphosphate phosphatase activity
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding
GO:0097023 fructose 6-phosphate aldolase activity
GO:0103026 fructose-1-phosphatase activity
Biological Process
GO:0006974 DNA damage response
GO:0030643 intracellular phosphate ion homeostasis
GO:1990748 cellular detoxification
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7u1y, PDBe:7u1y, PDBj:7u1y
PDBsum7u1y
PubMed35314193
UniProtQ9UT55|ART1A_SCHPO Damage-control phosphatase SPAC806.04c (Gene Name=SPAC806.04c)

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