Structure of PDB 7u1a Chain A Binding Site BS03

Receptor Information
>7u1a Chain A (length=617) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFPEGKPNCLLGLTIVFTGVLPTLERGASEALAKRYGARVTKSISSKTSV
VVLGDEAGPKKLEKIKQLKIKAIDEEGFKQLIAGMPAEGGEAAEKARRKL
EEQHNIATKEAELLVKKEEERSKKLAATVVREEDKLWTVKYAPTNLQQVC
GNKGSVMKLKNWLANWENSKKNSFKHAGKDGSGVFRAAMLYGPPGIGKTT
AAHLVAQELGYDILEQNASDVRSKTLLNAGVKNALDNMSVVGYFKHNEEA
QNLNGKHFVIIMDEVDGMSGGDRGGVGQLAQFCRKTSTPLILICNERNLP
KMRPFDRVCLDIQFRRPDANSIKSRLMTIAIREKFKLDPNVIDRLIQTTR
GDIRQVINLLSTISTTTKTINHENINEISKAWEKNIALKPFDIAHKMLDG
QIYSDIGSRNFTLNDKIALYFDDFDFTPLMIQENYLSTRPSVLKPGQSHL
EAVAEAANCISLGDIVEKKIRSSEQLWSLLPLHAVLSSVYPASKVAGHMA
GRINFTAWLGQNSKSAKYYRLLQEIHYHTRLGTSTDKIGLRLDYLPTFRK
RLLDPFLKQGADAISSVIEVMDDYYLTKEDWDSIMEFFVGPDVTTAIIKK
IPATVKSGFTRKYNSMT
Ligand information
Receptor-Ligand Complex Structure
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PDB7u1a A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		K195 G315 R476 H556 M660 G662 R663 I664
Binding residue
(residue number reindexed from 1)		K47 G154 R315 H395 M499 G501 R502 I503
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000278 mitotic cell cycle
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7u1a, PDBe:7u1a, PDBj:7u1a
PDBsum7u1a
PubMed35731107
UniProtP38630|RFC1_YEAST Replication factor C subunit 1 (Gene Name=RFC1)

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