Structure of PDB 7t3s Chain A Binding Site BS03

Receptor Information
>7t3s Chain A (length=210) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIHP
PNKFYSLNSTTGKIRTTHVMLDRENPDPVEAELMRKIIVSVTDCGRPPLK
ATSSATVFVNLLDLNDNDPTFRNLPFVAEILEGTPAGVSVYQVVAIDLDE
GLNGLVSYRMQDFVINSTSGVVTTTAELDRERIAEYQLRVVASDAGTPTK
SSTSTLTVRV
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7t3s Chain A Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7t3s Crystal Structure of Mouse Cadherin-23 EC8-9
Resolution2.966 Å
Binding residue
(original residue number in PDB)		E766 E820 D859 L860 D862 D895
Binding residue
(residue number reindexed from 1)		E20 E74 D113 L114 D116 D149
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7t3s, PDBe:7t3s, PDBj:7t3s
PDBsum7t3s
PubMed
UniProtQ99PF4|CAD23_MOUSE Cadherin-23 (Gene Name=Cdh23)

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