Structure of PDB 7oar Chain A Binding Site BS03

Receptor Information

>7oar Chain A (length=442) Species: 56957 (Thermus oshimai) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

EGLSSEQQRAFLAVTQTPHPAHLITGPAGTGKTTLLYALQKFYKGRAVTL
APTGTAALQARGQTVHSFFRFPARLLRYRHPEDIRPPGPHSPLRKAIEQM
EVLILDEVGMVRVDLLEAMDWALRKTRKRLEEPFGGVKVLLLGDTRQLEP
VVPGGEEALYIARTWGGPFFFQAHVWEEVALRVHRLWESQRQREDPLFAE
LLKRLRQGDPQALETLNRAAVRPDGGEEPGTLILTPRRKEADALNLKRLE
ALPGKPLEYQAQVKGEFAETDFPTEAALTLKKGAQVILLRNDPLGEYFNG
DLGWVEDLEAEALAVRLKRNGRRVVIRPFVWEKIVYTYDSEREEIKPQVV
GTFRQVPVRLAWALTVHKAQGLTLDKVHLELGRGLFAHGQLYVALTRVRR
LQDLSLSRPIAPTELLWRPEVEVFETRIQEGIWQKSHGWPSL

Ligand information

Ligand ID

ALF

InChI

InChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4

InChIKey

UYOMQIYKOOHAMK-UHFFFAOYSA-J

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	F[Al-](F)(F)F

Formula

Al F4

Name

TETRAFLUOROALUMINATE ION

PDB chain

7oar Chain A Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7oar Structural mechanism underpinning Thermus oshimai Pif1-mediated G-quadruplex unfolding.
Resolution	2.58 Å
Binding residue (original residue number in PDB)	A93 G94 K97 Q212 R256 G436 R462
Binding residue (residue number reindexed from 1)	A28 G29 K32 Q147 R191 G371 R397
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003678	DNA helicase activity
GO:0016887	ATP hydrolysis activity

	Biological Process
GO:0000723	telomere maintenance
GO:0006281	DNA repair

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Molecular Function

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Biological Process

External links

PDB	RCSB:7oar, PDBe:7oar, PDBj:7oar
PDBsum	7oar
PubMed	35736675
UniProt	K7RJ88

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