Structure of PDB 7n94 Chain A Binding Site BS03

Receptor Information
>7n94 Chain A (length=232) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HITILTLNINGLNSAIKRHRLASWIKSQDPSVCCIQETHLTCRDTHRLKI
KGWRKIYQANGKQKKAGVAILVSDKTDFKPTKIKRDKEGHYIMVKGSIQQ
EELTILNIYAPNTGAPRFIKQVLSDLQRDLDSHTLIMGAFNTPLSTLDRS
TRQKVNKDTQELNSALHQADLIDIYRTLHPKSTEYTFFSAPHHTYSKIDH
IVGSKALLSKCKRTEIITNKLSDHSAIKLELR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7n94 Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease.
Resolution2.85 Å
Binding residue
(original residue number in PDB)		R60 I62 Y63 R91
Binding residue
(residue number reindexed from 1)		R54 I56 Y57 R85
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
3.1.21.-
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:7n94, PDBe:7n94, PDBj:7n94
PDBsum7n94
PubMed34554261
UniProtO00370|LORF2_HUMAN LINE-1 retrotransposable element ORF2 protein

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