Structure of PDB 7n5w Chain A Binding Site BS03

Receptor Information
>7n5w Chain A (length=85) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LGSAFQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLK
VHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7n5w Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7n5w Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
Resolution2.24 Å
Binding residue
(original residue number in PDB)		C412 C415 H428 H432
Binding residue
(residue number reindexed from 1)		C36 C39 H52 H56
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7n5w, PDBe:7n5w, PDBj:7n5w
PDBsum7n5w
PubMed36626981
UniProtO95365|ZBT7A_HUMAN Zinc finger and BTB domain-containing protein 7A (Gene Name=ZBTB7A)

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