Structure of PDB 7lo5 Chain A Binding Site BS03

Receptor Information
>7lo5 Chain A (length=1016) Species: 980427 (Deinococcus wulumuqiensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLQLVKKFQKRLEDIVAYGGTRNESSVRAAFQQLLSDWAEGSGLRLITEV
TQKAVAGNNVRPDGTLKDSLQQSRGYWESKDEADTLDDEIQKKLAKGYPR
DNIIFEDSRLAVLMQNGEEVQRVDMGDAGALAGLLKLFFEFEPPQVLEFR
KAVDHFKDEMPHLLKILREAADAAEQKADYRGERDHFVEIAKEAINPDFS
PRDAREMLIQHILTGDLFTSVFDNAQYHEDNNIAQQLQQLAATFYKGPVK
RDIAERTKRYYGAIQAAAAQIADHHEKQRFLKALYENFYRAYNPAGAERL
GIFYTPGEIVRFMIEATDTLLEKHFQKELADKGVEILDPATGTGTFITEL
IDFLPKAKLEQKYREELHCNELALLPYYIANLNIEATYAQKMGRYEEFRN
IVLVDTLDNTGFSGLFGSVTAENLERAKRQNARPVRVIIGNPPYRANQAN
ENDNNKNREYKEIDRRIKATYVAASTAQKTKLYDMYSRFLRWATDRLKED
GIVAFVSNSSFIDSRTFDGFRKEVVKDFDHIYILDMKGNANTSGERRKRE
GGNVFNDQIKVGVAVYFLVRSAKDTKIWYHAVPDFWRAREKLEWLKTTKF
EDIEFDHIRPDAKHNWLGQVDEENDWNEFLPVADKDTKQAKGLGQERAIF
KLYSLGVVTNRDEWVYSRAEDELADKVRYFIGRYNEIIKLPLGDLMSRNW
EGDIKMTRATIADAQSRKSYSLEKNSIVPSLYRPFDVLKMYFSKNLNEMQ
YQMPSIFPKGVGENVVIALSGSPAAKPFQVLATDILPSLDLLEKTQCLPF
YRYTMNGERLNNITDYALKAFQTHYADTSISREDIFHYVYAVLHHPAYRE
KYALNLRQEFPRIPFYPEFGRWAAWGRELMALHIGFESVAPYPLKRTDEP
PKNDTPEALALAKKARLKVQRDAAKQPTGAVELDGLTTLAGIPAAAWAYK
LGNRSALEWVLERHKETTPKDATIREKFNTYRFADHKERVIDLLARVTTV
SVETVRIVGEMPAETM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lo5 Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		E25 S26 N60 R62 Y99
Binding residue
(residue number reindexed from 1)		E24 S25 N59 R61 Y98
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0008168 methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7lo5, PDBe:7lo5, PDBj:7lo5
PDBsum7lo5
PubMed33826880
UniProtA0A345IJ72

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