Structure of PDB 7l49 Chain A Binding Site BS03

Receptor Information
>7l49 Chain A (length=522) Species: 32644 (unidentified) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTITKTLKLRIVRPYNSAEVEKIVADEKNNREKIALEKNKDKVKEACSKH
LKVAAYCTTQVERNACLFCKARKLDDKFYQKLRGQFPDAVFWQEISEIFR
QLQKQAAEIYNQSLIELYYEIFIKGKGIANASSVEHYLSDVCYTRAAELF
KNAAIASGLRSKIKSNFRLKELKNMKSGLPTTKSDNFPIPLVKQKGGQYT
GFEISNHNSDFIIKIPFGRWQVKKEIDKYRPWEKFDFEQVQKSPKPISLL
LSTQRRKRNKGWSKDEGTEAEIKKVMNGDYQTSYIEVKRGSKICEKSAWM
LNLSIDVPKIDKGVDPSIIGGIDVGVKSPLVCAINNAFSRYSISDNDLFH
FNKKMFARRRILLKKNRHKRAGHGAKNKLKPITILTEKSERFRKKLIERW
ACEIADFFIKNKVGTVQMENLESMKRKEDSYFNIRLRGFWPYAEMQNKIE
FKLKQYGIEIRKVAPNNTSKTCSKCGHLNNYFNFEYRKKNKFPHFKCEKC
NFKENADYNAALNISNPKLKST
Ligand information
>7l49 Chain E (length=135) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccgcuucaccaauugagugaaggugggcugcuugcaucagccuaaugucg
agaagugcuuucuucggaaaguaacccucgaaacaaauucauuuagacga
augaaggaaugcaacaguugacccaacgucgccgg
...<<<<<<<<..>>.>>>>>>...(((((.<<<<<<))))).....<<<
<<..<<<<<<<<<..>>>>>>>.>>.>>>>>.....<<<<.<<..>>.>>
>>......>>>>>>.....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7l49 Structural basis for substrate recognition and cleavage by the dimerization-dependent CRISPR-Cas12f nuclease.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		T7 K8 T9 R13 V15 R16 K31 R66 N67 C72 K73 K76 D79 Y82 F94 W95 S99 Y113 N169 G181 P183 P191 D213 S255 T256 Q257 R258 R259 R261 N262 K263 T271 E272 E289 K291 K295 K299 S300 N305 R363 L365 L366 K367 N369 R370 K372 R373 A374 G375 H376 G377 A378 N380 K381 R394 F395 K398 E401 C405 N436 I437 F454 K455
Binding residue
(residue number reindexed from 1)		T4 K5 T6 R10 V12 R13 K28 R63 N64 C69 K70 K73 D76 Y79 F91 W92 S96 Y110 N166 G178 P180 P188 D210 S252 T253 Q254 R255 R256 R258 N259 K260 T268 E269 E286 K288 K292 K296 S297 N302 R360 L362 L363 K364 N366 R367 K369 R370 A371 G372 H373 G374 A375 N377 K378 R391 F392 K395 E398 C402 N433 I434 F451 K452
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