Structure of PDB 7kr4 Chain A Binding Site BS03 |
| >7kr4 Chain A (length=639) Species: 9606 (Homo sapiens)
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SNDMDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLR
MVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKA
VAQATGRQLESVRAEAAEKGDVGLVAENSRSTPPPPLTASGVFSKFRDIA
RLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAA
LSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPD
LDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAA
FTCEYKYDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPS
VTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDL
IYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLE
QSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVI
GAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSL
KALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLV
DSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQS |
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| PDB | 7kr4 High-fidelity DNA ligation enforces accurate Okazaki fragment maturation during DNA replication. |
| Resolution | 2.2 Å |
Binding residue
(original residue number in PDB) | R305 T415 G416 S417 A418 T420 R451 G453 A455 Q457 S458 H546 Q636 T639 T640 R641 K642 R643 R768 G769 K770 R771 G776 C794 K795 G797 S850 L851 S852 P853 Y855 S869 L870 F872 |
Binding residue
(residue number reindexed from 1) | R48 T153 G154 S155 A156 T158 R189 G191 A193 Q195 S196 H284 Q374 T377 T378 R379 K380 R381 R506 G507 K508 R509 G514 C532 K533 G535 S588 L589 S590 P591 Y593 S607 L608 F610 |
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| Enzyme Commision number |
6.5.1.1: DNA ligase (ATP). |
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