Structure of PDB 7kqn Chain A Binding Site BS03

Receptor Information
>7kqn Chain A (length=596) Species: 7070 (Tribolium castaneum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVHYYRLSLKSRQKAPKIVNSKYNSILNIALKNFRLCKKHKTKKPVQILA
LLQEIIPKSYFGTTTNLKRFYKVVEKILTQSSFECIHLSVLHKCYDYDAI
PWLQNVEPNLRPKLLLKHNLFLLDNIVKPIIAFYYKPIKTLNGHEIKFIR
KEEYISFESKVFHKLKKMKYLVEVQDEVKPRGVLNIIPKQDNFRAIVSIF
PDSARKPFFKLLTSKIYKVLEEKYKTSGSLYTCWSEFTQKTQGQIYGIKV
DIRDAYGNVKIPVLCKLIQSIPTHLLDSEKKNFIVDHISNQFVAFRRKIY
KWNHGLLQGDPLSGCLCELYMAFMDRLYFSNLDKDAFIHRTVDDYFFCSP
HPHKVYDFELLIKGVYQVNPTKTRTNLPTHRHPQDEIPYCGKIFNLTTRQ
VRTLYKLPPNYEIRHKFKLWNFNNQISDDNPARFLQKAMDFPFICNSFTK
FEFNTVFNDQRTVFANFYDAMICVAYKFDAAMMALRTSFLVNDFGFIWLV
LSSTVRAYASRAFKKIVTYKGGKYRKVTFQCLKSIAWRAFLAVLKRRTEI
YKGLIDRIKSREKLTMKFHDGEVDASYFCKLPEKFRFVKINRKASI
Ligand information
Receptor-Ligand Complex Structure
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PDB7kqn Flexibility of telomerase in binding the RNA template and DNA telomeric repeat.
Resolution2.02 Å
Binding residue
(original residue number in PDB)		N424 R433 Q436 K437 D440 P442
Binding residue
(residue number reindexed from 1)		N424 R433 Q436 K437 D440 P442
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003964 RNA-directed DNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006278 RNA-templated DNA biosynthetic process
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005694 chromosome
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7kqn, PDBe:7kqn, PDBj:7kqn
PDBsum7kqn
PubMed34969861
UniProtQ0QHL8

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