Structure of PDB 7eu9 Chain A Binding Site BS03

Receptor Information
>7eu9 Chain A (length=1078) Species: 1410628 (Lachnospiraceae bacterium ND2006) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NASETRKAYTTKMIPRSHDRMKLLGNFMDYLMDGTPIFFELWNQFGGGID
RDIISGTANKDKISDDLLLAVNWFKVMPINSKPQGVSPSNLANLFQQYSG
SEPDIQAQEYFASNFDTEKHQWKDMRVEYERLLAELQLSRSDMHHDLKLM
YKEKCIGLSLSTAHYITSVMFGTGAKNNRQTKHQFYSKVIQLLEESTQIN
SVEQLASIILKAGDCDSYRKLRIRCSRKGATPSILKIVQDYELGTNHDDE
VNVPSLIANLKEKLGRFEYECEWKCMEKIKAFLASKVGPYYLGSYSAMLE
NALSPIKGMTTKNCKFVLKQIDAKNDIKYENEPFGKIVEGFFDSPYFESD
TNVKWVLHPHHIGESNIKTLWEDLNAIHSKYEEDIASLSEDKKEKRIKVY
QGDVCQTINTYCEEVGKEAKTPLVQLLRYLYSRKDDIAVDKIIDGITFLS
KKHKVEKQKINPVIQKYPSFNFGNNSKLLGKIISPKDKLKHNLKCNRNQV
DNYIWIEIKVLNTKTMRWEKHHYALSSTRFLEEVYYPATSENPPDALAAR
FRTKTNGYEGKPALSAEQIEQIRSAPVGLRKVKKRQMRLEAARQQNLLPR
YTWGKDFNINICKRGNNFEVTLATKVKKKKEKNYKVVLGYAANIVRKNTY
AAIEAHANGDGVIDYNDLPVKPIESGFVTVESQVRDKSYDQLSYNGVKLL
YCKPHVESRRSFLEKYRNGTMKDNRGNNIQIDFMKDFEAIADDETSLYYF
NMKYCKLLQSSIRNHSSQAKEYREEIFELLRDGKLSVLKLSSLSNLSFVM
FKVAKSLIGTYFGHLLKKPKAPPITDEDKQKADPEMFALRLALEEKRLNK
VKSKKEVIANKIVAKALELRDKYGPVLIKGENISDTTKKGKKSSTNSFLM
DWLARGVANKVKEMVMMHQGLEFVEVNPNFTSHQDPFVHKNPENTFRARY
SRCTPSELTEKNRKEILSFLSDKPSKRPTNAYYNEGAMAFLATYGLKKND
VLGVSLEKFKQIMANILHQRSEDQLLFPSRGGMFYLATYKLDADATSVNW
NGKQFWVCNADLVAAYNVGLVDIQKDFK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7eu9 Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Resolution2.35 Å
Binding residue
(original residue number in PDB)
H170 Y171 S174 G178 G180 A181 K182 N183 K188 K234 G235 A236 P238 S239 K269 I650 V651 R652 Y755 I896 F911 L912 W915 N940 P941 N942 F943 S945 H946 R962 R990 P991 T992
Binding residue
(residue number reindexed from 1)
H164 Y165 S168 G172 G174 A175 K176 N177 K182 K228 G229 A230 P232 S233 K263 I644 V645 R646 Y749 I883 F898 L899 W902 N927 P928 N929 F930 S932 H933 R949 R977 P978 T979
External links