Structure of PDB 7d4s Chain A Binding Site BS03

Receptor Information
>7d4s Chain A (length=345) Species: 550 (Enterobacter cloacae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MELQPQFNEFLANIRPTDTQKEDWKSGARTLRERLKNFEPLKEIVVSTFL
QGSIRRSTAIRPLGDKRPDVDIVVVTNLDHTRMSPTDAMDLFIPFLEKYY
PGKWETQGRSFGITLSYVELDLVITAIPESGAEKSHLEQLYKSESVLTVN
SLEEQTDWRLNKSWTPNTVEDAPASEWKAHPLVLPDREKNEWGRTHPLAQ
IRWTAEKNRLCNGHYINLVRAVKWWRQQNSEDLPKYPKGYPLEHLIGNAL
DNGTTSMAQGLVQLMDTFLSRWAAIYNQKSKPWLSDHGVAEHDVMARLTA
EDFCSFYEGIASAAEIARNALASEEPQESAQLWRQLFGSKFPLPG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7d4s Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7d4s Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Resolution1.93 Å
Binding residue
(original residue number in PDB)
D69 D71
Binding residue
(residue number reindexed from 1)
D69 D71
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
GO:0051607 defense response to virus

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Molecular Function

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Biological Process
External links
PDB RCSB:7d4s, PDBe:7d4s, PDBj:7d4s
PDBsum7d4s
PubMed33836064
UniProtP0DSP4|CDND2_ENTH5 Cyclic AMP-AMP-GMP synthase (Gene Name=cdnD02)

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