Structure of PDB 7cym Chain A Binding Site BS03

Receptor Information
>7cym Chain A (length=417) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFSGPLKPMTFSIYEGQEPSQIIFQFKANPPAVTFELTGETDNIFVIERE
GLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDINDNRPT
FLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMIN
NVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFS
DTTSVDIIVTENIWKAPKPVEMVENSTDPHPIKITQVRWNDPGAQYSLVD
KEKLPRFPFSIDQEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLE
IHVKVKDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANS
FLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLKKQDTPQYNLTIEVS
DKDFKTLCFVQINVIDE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7cym Chain A Residue 505 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7cym Mechanism of dimerization and structural features of human LI-cadherin.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		E40 D85 E87 D121
Binding residue
(residue number reindexed from 1)		E15 D60 E62 D96
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cym, PDBe:7cym, PDBj:7cym
PDBsum7cym
PubMed34364873
UniProtQ12864|CAD17_HUMAN Cadherin-17 (Gene Name=CDH17)

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