Structure of PDB 7cec Chain A Binding Site BS03

Receptor Information
>7cec Chain A (length=553) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALP
LQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQG
PGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWS
FCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQDG
PYEVGPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRD
MKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDG
EVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDI
AVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRN
SYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGI
CLQVKSCFEYTANPAGYNPSISIVGTLEAEKESSRVQFRKYTQELTLKRQ
KQKVCMEETLWLQDNLRPIPITASVEIQEPLPEVLPILNSDEPKTAHIDV
HFL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7cec Chain A Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7cec Structural mechanism of laminin recognition by integrin.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		D418 D420 N422 Y424 D426 S441
Binding residue
(residue number reindexed from 1)		D396 D398 N400 Y402 D404 S419
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0008305 integrin complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7cec, PDBe:7cec, PDBj:7cec
PDBsum7cec
PubMed34188035
UniProtP23229|ITA6_HUMAN Integrin alpha-6 (Gene Name=ITGA6)

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