Structure of PDB 7c7l Chain A Binding Site BS03

Receptor Information
>7c7l Chain A (length=503) Species: 115547 (uncultured archaeon) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNTITKTLKLRIVRPYNSAEVEKIVADEKNNREKIALKEACSKHLKVTTQ
VERNACLFCKARKLDDKFYQKLRGQFPDAVFWQEISEIFRQLQKQAAEIY
NQSLIELYYEIFIKGKGIANASSVEHYLSDVCYTRAAELFKNAAIASGLR
SKIKSNFRLKELKNMKSGLPTTKSDNFPIPLVKQKGGQYTGFEISNHNSD
FIIKIPFGRWQVKKEIDKYRPWEKFDFEQVQKSPKPISLLLSTQRRKRNK
GWSKDEGTEAEIKKVMNGDYQTSYIEVKRGSKIGEKSAWMLNLSIDVPKI
DKGVDPSIIGGIAVGVKSPLVCAINNAFSRYSISDNDLFHFNKKMFARRR
ILLKKNRHKRAGHGAKNKLKPITILTEKSERFRKKLIERWACEIADFFIK
NKVGTVQMENLESMKRKEDSYFNIRLWPYAEMQNKIEFKLKQYGIEIRKV
APNNTSKTCSKCGHLNNYFNFEYRKKNKFPHFKCEKCNADYNAALNISNP
KLK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7c7l Structure of the miniature type V-F CRISPR-Cas effector enzyme.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		I131 N133 S135 S136 H139 Y140 S142 Y146 A156 R163 K173 K176 K179 Q242 V243 Q244
Binding residue
(residue number reindexed from 1)		I118 N120 S122 S123 H126 Y127 S129 Y133 A143 R150 K160 K163 K166 Q229 V230 Q231
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7c7l, PDBe:7c7l, PDBj:7c7l
PDBsum7c7l
PubMed33333018
UniProtA0A482D308|CS12F_UNCAX CRISPR-associated endodeoxyribonuclease Cas12f1 (Gene Name=cas12f)

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