Structure of PDB 7c1o Chain A Binding Site BS03

Receptor Information

>7c1o Chain A (length=301) Species: 224324 (Aquifex aeolicus VF5)

MKVGYVAIVGKPNVGKSTLLNNLLGTKVSIISPKAGTTRMRVLGVKNIPN
EAQIIFLDTPGIAEPKKSDVLGHSMVEIAKQSLEEADVILFMIDATEGWR
PRDEEIYQNFIKPLNKPVIVVINKIDKIGPAKNVLPLIDEIHKKHPELTE
IVPISALKGANLDELVKTILKYLPEGEPLFPEDMITDLPLRLLAAEIVRE
KAMMLTREEVPTSIAVKINEIKPGDANPNMLVIKGEIIVDRENLKPIIIG
KKGQRLKEIGKRARQELELILGRPVYLELWVKVVPDWRRRPEYVRLFGYA
L

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 7c1o Chain A Residue 405

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7c1o Crystal structure of Aquifex aeolicus Era Y63A bound to GDP.AlF4-
• Resolution: 2.18 Å
• Binding residue (original residue number in PDB): S17 T38
• Binding residue (residue number reindexed from 1): S17 T38
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003924 GTPase activity
• GO:0005525 GTP binding
• GO:0019843 rRNA binding
• GO:0043024 ribosomal small subunit binding
• GO:0070181 small ribosomal subunit rRNA binding

Biological Process

• GO:0000028 ribosomal small subunit assembly
• GO:0042254 ribosome biogenesis
• GO:0042274 ribosomal small subunit biogenesis

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005886 plasma membrane

External links

• PDB: RCSB:7c1o, PDBe:7c1o, PDBj:7c1o
• PDBsum: 7c1o
• UniProt: O67800|ERA_AQUAE GTPase Era (Gene Name=era)