Structure of PDB 7bke Chain A Binding Site BS03

Receptor Information

>7bke Chain A (length=447) Species: 323259 (Methanospirillum hungatei JF-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KSVPVEKTAMVVGGGVAGMQAALDLASAGIKTYLIERTPTIGGRMSQLDK
TFPTLDCSQCILTPKMVDVGRHPNIEMMTYTEVEKVEGYIGNFDVTLRKK
ARGVLTPTEATAKGIVGGGCNGCGDCSAVCPVIKPNPFEMGMAPRKAIYI
YHAQVMPLIYTVDFDSCVKCGLCVEACGDKKAIDLEMQDEFITVKVGTAV
LATGYELFPIENKREWGYKQFDNVINALEFERLICASGPTGGHLVRPSDG
KTPMKVGFVLCAGSRDNTGIGKPYCSRFCCMYSLKHAHQIMEKIPGAVAY
LFYMDIRSFGKMYEEFYYRIQHEGAKFIRGRVANVLEDKETKNLHVFTED
TLLGRPVDVEVDLLVLAAAVQPNEGANELRKKFGVSASQDGWMLEAHPKL
NPCGTTTAGVFLAGVCQGPKDIPDTVAQAEGAASAASIPIHMGEVEL

Ligand information

InChI=1S/4Fe.4S

LJBDFODJNLIPKO-UHFFFAOYSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 2.0.7	[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385	S1[Fe]S[Fe]1.S2[Fe]S[Fe]2

Formula

Fe4 S4

Name

IRON/SULFUR CLUSTER

ChEMBL

DrugBank

ZINC

PDB chain

7bke Chain A Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	7bke Three-megadalton complex of methanogenic electron-bifurcating and CO 2 -fixing enzymes.
Resolution	2.8 Å
Binding residue (original residue number in PDB)	C261 N262 G263 C264 G265 C267 Y301 C318 K321 I324
Binding residue (residue number reindexed from 1)	C120 N121 G122 C123 G124 C126 Y160 C177 K180 I183
Annotation score	4

Enzymatic activity

Enzyme Commision number

1.8.-.-

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0051539	4 iron, 4 sulfur cluster binding

View graph for
Molecular Function

External links

PDB	RCSB:7bke, PDBe:7bke, PDBj:7bke
PDBsum	7bke
PubMed	34516836
UniProt	Q2FKZ1

[Back to BioLiP]