Structure of PDB 7b4s Chain A Binding Site BS03

Receptor Information

>7b4s Chain A (length=217) Species: 561007 (Mycobacteroides abscessus ATCC 19977) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DQLIASVVPELLPSAELYEDPPGLEPLPEEEPLIAKSVAKRRNEFITVRY
CARQALSVLGIPEVPILKGDKGQPLWPDGIVGSMTHTEGFRGAVVGRTGE
VRSVGIDAEPHDVLPNGVLKSIALPVERDELDALPAGTHWDRLLFCAKET
TYKAWFPLTARWLGFEDAHITIDPDGTFTSRILVDGRANDGTVLSAFDGR
WIIDKGLILTAIVVPKL

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

7b4s Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7b4s Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds.
Resolution	1.38 Å
Binding residue (original residue number in PDB)	D111 E113 E153
Binding residue (residue number reindexed from 1)	D107 E109 E149
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000287	magnesium ion binding
GO:0008897	holo-[acyl-carrier-protein] synthase activity
GO:0016740	transferase activity
GO:0016780	phosphotransferase activity, for other substituted phosphate groups
GO:0046872	metal ion binding

	Biological Process
GO:0009237	siderophore metabolic process
GO:0009239	enterobactin biosynthetic process

	Cellular Component
GO:0009366	enterobactin synthetase complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7b4s, PDBe:7b4s, PDBj:7b4s
PDBsum	7b4s
PubMed	34508141
UniProt	B1MD73

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