Structure of PDB 7b1k Chain A Binding Site BS03

Receptor Information
>7b1k Chain A (length=200) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFSIRKIITISDYVTMLNIITGLLAILLNSFSLIYLSIIFDSLDGYVARK
TGTVSDFGAELDSISDVVSFGVAPAYLLYNNFESNLALISAIIFCLCGAL
RLARFGILNVKGFIGLPIPAGALLLVGFCQLINSYLINSILAILIGLLMI
SDIKYPKYPNKIFIYIFAVSLCLAIVGIPHFALMLCLIYAIYGIIKYIRG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7b1k Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7b1k Crystal structures of phosphatidyl serine synthase PSS reveal the catalytic mechanism of CDP-DAG alcohol O-phosphatidyl transferases
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D41 D62 S65 D66
Binding residue
(residue number reindexed from 1)		D41 D62 S65 D66
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.8.8: CDP-diacylglycerol--serine O-phosphatidyltransferase.
Gene Ontology
Molecular Function
GO:0003882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity
GO:0016740 transferase activity
GO:0016780 phosphotransferase activity, for other substituted phosphate groups
Biological Process
GO:0008654 phospholipid biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:7b1k, PDBe:7b1k, PDBj:7b1k
PDBsum7b1k
PubMed
UniProtQ58609|PSS_METJA CDP-diacylglycerol--serine O-phosphatidyltransferase (Gene Name=pssA)

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