Structure of PDB 7b0c Chain A Binding Site BS03

Receptor Information
>7b0c Chain A (length=144) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRLTKFTDLALRSLMRLAVVRDGDEPLATREVAEVVGVPYTHAAKAITRL
QHLGVVEARRGRGGGLTLTDLGRRVSVGWLVRELEGEAEVVDCEGDNPCP
LRGACRLRRALRDAQEAFYAALDPLTVTDLVAAPTGPVLLGLTD
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7b0c Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7b0c Structural determinants of DNA recognition by the NO sensor NsrR and related Rrf2-type [FeS]-transcription factors.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		V91 C93 C99 L101 C105 R108
Binding residue
(residue number reindexed from 1)		V91 C93 C99 L101 C105 R108
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7b0c, PDBe:7b0c, PDBj:7b0c
PDBsum7b0c
PubMed35908109
UniProtQ9L132|NSRR_STRCO HTH-type transcriptional repressor NsrR (Gene Name=nsrR)

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