Structure of PDB 7abn Chain A Binding Site BS03

Receptor Information
>7abn Chain A (length=496) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNRSALDFRHFVDHLRRQGDLVDVHTEVDANLEIGAITRRVYERRAPAPL
FHNIRDSLPGARVLGAPAGLRADRARAHSRLALHFGLPEHSGPRDIVAML
RAAMRAEPIAPRRLERGPVQENVWLGEQVDLTRFPVPLLHEQDGGRYFGT
YGFHVVQTPDGSWDSWSVGRLMLVDRNTLAGPTIPTQHIGIIREQWRRLG
KPTPWAMALGAPPAALAAAGMPLPEGVSEAGYVGALVGEPVEVVRTQTNG
LWVPANTEIVLEGEISLDETALEGPMGEYHGYSFPIGKPQPLFHVHALSF
RDQPILPICVAGTPPEENHTIWGTMISAQLLDVAQNAGLPVDMVWCSYEA
ATCWAVLSIDVQRLAALGTDAAAFAARVAETVFGSHAGHLVPKLILVGND
IDVTEIDQVVWALATRAHPLHDHFAFPQIRDFPMVPYLDAEDKARGSGGR
LVINCLYPEQFAGQMRAATASFRHAYPTALRRRVEERWSDYGFGDA
Ligand information
Ligand IDIMD
InChIInChI=1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)/p+1
InChIKeyRAXXELZNTBOGNW-UHFFFAOYSA-O
SMILES
SoftwareSMILES
CACTVS 3.341[nH]1cc[nH+]c1
ACDLabs 10.04c1c[nH+]cn1
OpenEye OEToolkits 1.5.0c1c[nH+]c[nH]1
FormulaC3 H5 N2
NameIMIDAZOLE
ChEMBL
DrugBank
ZINC
PDB chain7abn Chain A Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7abn Structure and Mechanism of Pseudomonas aeruginosa PA0254/HudA, a prFMN-Dependent Pyrrole-2-carboxylic Acid Decarboxylase Linked to Virulence.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		E278 Y279 N318 W322
Binding residue
(residue number reindexed from 1)		E278 Y279 N318 W322
Annotation score1
Enzymatic activity
Enzyme Commision number 4.1.1.93: pyrrole-2-carboxylate decarboxylase.
Gene Ontology
Molecular Function
GO:0008694 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GO:0016831 carboxy-lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006744 ubiquinone biosynthetic process
GO:0009056 catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7abn, PDBe:7abn, PDBj:7abn
PDBsum7abn
PubMed33763291
UniProtQ9I6N5|P2CDC_PSEAE Pyrrole-2-carboxylic acid decarboxylase (Gene Name=hudA)

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