Structure of PDB 6xnz Chain A Binding Site BS03

Receptor Information
>6xnz Chain A (length=550) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEK
VLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFR
YDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEK
HGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSVLCCKPLCLM
LADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYD
EKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYE
VWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIF
QLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMMMNGNFARKLM
TQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQ
YSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWAS
EGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6xnz Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		Q495 P499 H501 K608 H609 G610 K973 Q978
Binding residue
(residue number reindexed from 1)		Q37 P41 H43 K150 H151 G152 K515 Q520
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6xnz, PDBe:6xnz, PDBj:6xnz
PDBsum6xnz
PubMed32945578
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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