Structure of PDB 6wb6 Chain A Binding Site BS03

Receptor Information
>6wb6 Chain A (length=653) Species: 7130 (Manduca sexta) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSYKLCVPAAYMKDCEQMLEVPTKSKVALECVPARDRVECLSFVQQRQAD
FVPVDPEDMYVASKIPNQDFVVFQEYRTDEEPDAPFRYEAVIVVHKDLPI
NNLDQLKGLRSCHTGVNRNVGYKIPLTMLMKRAVFPKMNDHSISPKENEL
KALSTFFAKSCIVGKWSPDPKTNSAWKSQYSHLCSMCEHPERCDYPDNYS
GYEGALRCLAHNNGEVAFTKVIFTRKFFGLPVGTTPASPSNENPEEFRYL
CVDGSKAPITGKACSWAARPWQGLIGHNDVLAKLAPLREKVKQLADSGAA
DKPEWFTKVLGLSEKIHHVADNIPIKPIDYLNKANYTEVIERGHGAPELV
VRLCVTSNVALSKCRAMSVFAFSRDIRPILDCVQENSEDACLKSVQDNGS
DLASVDDMRVAAAAKKYNLHPVFHEVYGELKTPNYAVAVVKKGTAYNKID
DLRGKKSCHSSYSTFSGLHAPLFYLINKRAIQSDHCVKNLGEFFSGGSCL
PGVDKDDVSKLKKQCGSDSSAWKCLEEDRGDVAFVSSADLSHFDANQYEL
LCLNRDAGGRDVLSSFATCNVAMAPSRTWVAAKDFLSDVSIAHTPLSLAQ
MLATRPDLFNIYGEFLKNNNVIFNNAAKGLATTEKLDFEKFKTIHDVISS
CGL
Ligand information
Ligand IDCO3
InChIInChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
InChIKeyBVKZGUZCCUSVTD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)([O-])[O-]
ACDLabs 10.04
CACTVS 3.341		[O-]C([O-])=O
FormulaC O3
NameCARBONATE ION
ChEMBL
DrugBankDB14531
ZINC
PDB chain6wb6 Chain A Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6wb6 Structural insight into the novel iron-coordination and domain interactions of transferrin-1 from a model insect, Manduca sexta.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		Y90 T116 R120 N121 V122 Y204
Binding residue
(residue number reindexed from 1)		Y88 T114 R118 N119 V120 Y202
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0055037 recycling endosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6wb6, PDBe:6wb6, PDBj:6wb6
PDBsum6wb6
PubMed33197096
UniProtP22297|TRF_MANSE Transferrin

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