Structure of PDB 6w7e Chain A Binding Site BS03

Receptor Information
>6w7e Chain A (length=252) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KWKTVSTIFLVVVLYLIIGATVFKALEQPQEISQRTTIVIQREKFLRAHP
CVSDQELDELIQQIVAAINAGSHWDLGSSFFFAGTVITTIGFGNISPRTE
GGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKQTKIR
IISTIIFILFGCVLFVALPAVIFSALDAIYFVVITLTTIGFGDYVLDFYK
PVVWFWILVGLAYFAAVLSMIGDWLRVIAKKTKEAVGEFRAHAAEWTANV
TS
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain6w7e Chain B Residue 407 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6w7e K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Resolution3.29 Å
Binding residue
(original residue number in PDB)		T142 T251
Binding residue
(residue number reindexed from 1)		T89 T188
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w7e, PDBe:6w7e, PDBj:6w7e
PDBsum6w7e
PubMed33127683
UniProtP97438|KCNK2_MOUSE Potassium channel subfamily K member 2 (Gene Name=Kcnk2)

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