Structure of PDB 6v37 Chain A Binding Site BS03

Receptor Information
>6v37 Chain A (length=263) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NVMKWKTVSTIFLVVVLYLIIGATVFKALEQPQEISQRTTIVIQREKFLR
AHPCVSDQELDELIQQIVAADNASHWDLGSSFFFAGTVITTIGFGNISPR
TEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFQTKIR
IISTIIFILFGCVLFVALPAVIFKHIEGWSALDAIYFVVITLTTIGFGDY
VAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVIAKKTKEAV
GEFRAHAAEWTAN
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain6v37 Chain A Residue 408 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6v37 Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		T142 I143 T251 I252 G253
Binding residue
(residue number reindexed from 1)		T91 I92 T194 I195 G196
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6v37, PDBe:6v37, PDBj:6v37
PDBsum6v37
PubMed32059793
UniProtP97438|KCNK2_MOUSE Potassium channel subfamily K member 2 (Gene Name=Kcnk2)

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