Structure of PDB 6v36 Chain A Binding Site BS03

Receptor Information
>6v36 Chain A (length=255) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTVSTIFLVVVLYLIIGATVFKALEQPQEISQRTTIVIQREKFLRAHPCV
SDQELDELIQQIVAADNAHWDLGSSFFFAGTVITTIGFGNISPRTEGGKI
FCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWQTKIRIIS
TIIFILFGCVLFVALPAVIFKHIEGWSALDAIYFVVITLTTIGFGDYVAG
GDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVIAKKTKEAVGEFRAHAAE
WTANV
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain6v36 Chain A Residue 408 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6v36 Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		I143 G144 F145 I252 G253
Binding residue
(residue number reindexed from 1)		I86 G87 F88 I192 G193
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6v36, PDBe:6v36, PDBj:6v36
PDBsum6v36
PubMed32059793
UniProtP97438|KCNK2_MOUSE Potassium channel subfamily K member 2 (Gene Name=Kcnk2)

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