Structure of PDB 6tz2 Chain A Binding Site BS03

Receptor Information
>6tz2 Chain A (length=1208) Species: 110829 (Bombyx mori cypovirus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TELYNTIFSETRKFTRESFKEIEHLTAKLANDRVARHDFLFNNSIALISD
YSGEDSNGNQLQATVTIPNEITNPKEYDPSDYPLAEDESFFKQGHKYDYL
VTFRAGSLTNTYEPKTKMYKLHAALDKLMHVKQRKSRFADLWRELCAVIA
SLDVWYQTTNYPLRTYVKLLFHKGDEFPFYESPSQDKIIFNDKSVASILP
TFVYTCCQVGTAIMSGILTHVESIVAMNHFLHCAKDSYIDEKLKIKGIGR
SWYQEALHNVGRATVPVWSQFNEVIGHRTKTTSEPHFVSSTFISLRAKRA
ELLYPEFNEYINRALRLSKTQNDVANYYAACRAMTNDGTFLATLTELSLD
AAVFPRIEQRLVTRPAVLMSNTRHESLKQKYANGVGSIAQSYLSSFTDEI
AKRVNGIHHDEAWLNFLTTSSPGRKLTEIEKLEVGGDVAAWSNSRIVMQA
VFAREYRTPERIFKSLKAPIKLVERQQSDRRQRAISGLDNDRLFLSFMPY
TIGKQIYDLNDNAAQGKQAGNAFDIGEMLYWTSQRNVLLSSIDVAGMDAS
VTTNTKDIYNTFVLDVASKCTVPRFGPYYAKNMEVFEVGKRQSQVKYVNA
AWQACALEAANSQTSTSYESEIFGQVKNAEGTYPSGRADTSTHHTVLLQG
LVRGNELKRASDGKNSCLTTIKILGDDIMEIFQGNENDTHDHAVSNASIL
NESGFATTAELSQNSIVLLQQLVVNGTFWGFADRISLWTREDTKDIGRLN
LAMMELNALIDDLLFRVRRPEGLKMLGFFCGAICLRRFTLSVDNKLYDST
YNNLSKYMTLVKYDKNPDFDSTLMSLILPLAWLFMPRGGEYPAYPFERRD
GTFTEDESMFTARGAYKRRLLYDVSNIREMIQQNSMVLDDDLLHEYGFTG
ALLLIDLNILDLIDEVKKEDISPVKVNELATSLEQLGKLGEREKSRRAAS
DLKIRGHALSNDIVYGYGLQEKIQKSAMATKETTVQSKRVSSRLHEVIVA
KTRDYKIPTMPADALHLYEFEVEDVTVDLLPHAKHTSYSNLAYNMSFGSD
GWFAFALLGGLDRSANLLRLDVASIRGNYHKFSYDDPVFKQGYKIYKSDA
TLLNDFFVAISAGPKEQGILLRAFAYYSLYGNVEYHYVLSPRQLFFLSDN
PVSAERLVRIPPSYYVSTQCRALYNIFSYLHILRSITSNQGKRLGMVLHP
GLIAYVRG
Ligand information
>6tz2 Chain T (length=36) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6tz2 Conservative transcription in three steps visualized in a double-stranded RNA virus.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		F420 T423 S425 P426 N447 V477 I489 Y504 Q519 Q522 R641 R841 V1142 P1145
Binding residue
(residue number reindexed from 1)		F416 T419 S421 P422 N443 V473 I485 Y500 Q515 Q518 R637 R837 V1138 P1141
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0019079 viral genome replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6tz2, PDBe:6tz2, PDBj:6tz2
PDBsum6tz2
PubMed31695188
UniProtQ993A4

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