Structure of PDB 6s5f Chain A Binding Site BS03

Receptor Information
>6s5f Chain A (length=188) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IWLYQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIE
PGKRIKLQIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEW
LEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRHEAEKLAAAYGMKYIETS
ARDAINVEKAFTDLTRDIYELVKRGEITIQEGWEGVKS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6s5f Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6s5f Structure of the human RAB39B in complex with GMPPNP
Resolution1.7 Å
Binding residue
(original residue number in PDB)		S22 T40
Binding residue
(residue number reindexed from 1)		S19 T37
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0031489 myosin V binding
Biological Process
GO:0006914 autophagy
GO:0010506 regulation of autophagy
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0032482 Rab protein signal transduction
GO:0050808 synapse organization
Cellular Component
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0031982 vesicle
GO:0043005 neuron projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6s5f, PDBe:6s5f, PDBj:6s5f
PDBsum6s5f
PubMed
UniProtQ96DA2|RB39B_HUMAN Ras-related protein Rab-39B (Gene Name=RAB39B)

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