Structure of PDB 6s22 Chain A Binding Site BS03

Receptor Information
>6s22 Chain A (length=529) Species: 59729 (Taeniopygia guttata) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HCLPGHYTPVELKPFLDRPLQDPNAPGASGKAFKTINLNSEEQKEKQAGE
EKHCFNAFASDRISLHRDLGPDTRPPECIEQKFKRCPPLPTTSIIIVFHN
EAWSTLLRTVHSVMYTSPAILLKEIILVDDASVDEYLHDKLDEYVKQFQI
VKVVRQKERKGLITARLLGASVATGETLTFLDAHCECFYGWLEPLLARIA
ENPVAVVSPDIASIDLNTFEFSKPSPYGHSHNRGNFDWSLSFGWESLPKH
ENKRRKDETYPIRTPTFAGGLFSISKDYFEYIGSYDEEMEIWGGENIEMS
FRVWQCGGQLEIMPCSVVGHVFRSGTQVITRNQVRLAEVWMDEYKEIFYR
RNTEAAKIVKQKTFGDISKRIDLRQRLQCKNFTWYLSNVYPEAYVPDLNP
LFSGYLKNIGNRMCLDVGENNHGGKPLIMYSCHGLGGNQYFEYSAHHEIR
HNIQKELCLHASKGPVQLRECTYKGQKTFAVGEEQWLHQKDQTLYNEALH
MCLTGNGEHPSLASCNPSDPFQKWIFGQN
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain6s22 Chain A Residue 717 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6s22 Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3.
Resolution1.96 Å
Binding residue
(original residue number in PDB)		D275 H277 H413
Binding residue
(residue number reindexed from 1)		D182 H184 H320
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.41: polypeptide N-acetylgalactosaminyltransferase.
External links
PDB RCSB:6s22, PDBe:6s22, PDBj:6s22
PDBsum6s22
PubMed31932717
UniProtH0ZAB5|GALT3_TAEGU Polypeptide N-acetylgalactosaminyltransferase 3 (Gene Name=GALNT3)

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