Structure of PDB 6s07 Chain A Binding Site BS03

Receptor Information
>6s07 Chain A (length=303) Species: 471852 (Thermomonospora curvata DSM 43183) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMPSFDFDIPRRSPQEIAKGMVAIPGGTFRMGGEDPDAFPEDGEGPVRTV
RLSPFLIDRYAVSNRQFAAFVKATGYVTDAERYGWSFVFHAHVAPGTPVM
DAVVPEAPWWVAVPGAYWKAPEGPGSSITDRPNHPVVHVSWNDAVAYATW
AGKRLPTEAEWEMAARGGLDQARYPWGNELTPRGRHRCNIWQGTFPVHDT
GEDGYTGTAPVNAFAPNGYGLYNVAGNVWEWCADWWSADWHATESPATRI
DPRGPETGTARVTKGGSFLCHESYCNRYRVAARTCNTPDSSAAHTGFRCA
ADP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6s07 Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6s07 Structure of formylglycine-generating enzyme in complex with copper and a substrate reveals an acidic pocket for binding and activation of molecular oxygen.
Resolution1.04 Å
Binding residue
(original residue number in PDB)		N222 V223 G225 V227 E229 G264
Binding residue
(residue number reindexed from 1)		N223 V224 G226 V228 E230 G265
Annotation score1
Enzymatic activity
Enzyme Commision number 1.8.3.7: formylglycine-generating enzyme.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0120147 formylglycine-generating oxidase activity
GO:1903136 cuprous ion binding
Biological Process
GO:0018158 protein oxidation
GO:0043687 post-translational protein modification

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Molecular Function
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Biological Process
External links
PDB RCSB:6s07, PDBe:6s07, PDBj:6s07
PDBsum6s07
PubMed31588272
UniProtD1A7C3|FGE_THECD Formylglycine-generating enzyme (Gene Name=Tcur_4811)

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