Structure of PDB 6r7u Chain A Binding Site BS03

Receptor Information
>6r7u Chain A (length=307) Species: 28112 (Tannerella forsythia) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTCGSELNMEQIRRTEPLKYQRITDWENQIKLHSRSVPSSTILIPVVVHV
VYNNSAQNISDAQIISQIQVLNEDFRRMNADQANTPSAFANLAGNANIEF
KLARRDPNGNTTNGITRTSTSTETFSMEMDNVKFSNLGGNNAWNTRRYLN
IWVCNLGDDLLGYAQFPFEFQTKPNTDGVVIHYKHFGRDGSAESPYDKGR
TATHAVGHWLDLRHIWGDDGGSCSGTDNIADTPNQGGYNEGCPSFPKTDH
CTNTSPGVMFMNYMDYTYDACMNLFTKGQVERMRSLFDTQTGIRREMQIY
ANELTNP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6r7u Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6r7u Structure-based mechanism of cysteine-switch latency and of catalysis by pappalysin-family metallopeptidases.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		C23 H224 H228 H234
Binding residue
(residue number reindexed from 1)		C3 H204 H208 H214
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:6r7u, PDBe:6r7u, PDBj:6r7u
PDBsum6r7u
PubMed31949901
UniProtG8ULV1

[Back to BioLiP]