Structure of PDB 6ot3 Chain A Binding Site BS03

Receptor Information
>6ot3 Chain A (length=357) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQA
LGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAELDA
LEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRW
AESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKS
PFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRTSGAGGQHVN
RTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNA
EKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQ
FIEASLK
Ligand information
Receptor-Ligand Complex Structure
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PDB6ot3 The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		G137 T139 E140 S205 R212 R213 H214 T215
Binding residue
(residue number reindexed from 1)		G132 T134 E135 S200 R207 R208 H209 T210
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
Biological Process
GO:0006412 translation
GO:0006415 translational termination
GO:0075523 viral translational frameshifting
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ot3, PDBe:6ot3, PDBj:6ot3
PDBsum6ot3
PubMed31189921
UniProtP07012|RF2_ECOLI Peptide chain release factor RF2 (Gene Name=prfB)

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