Structure of PDB 6osq Chain A Binding Site BS03

Receptor Information
>6osq Chain A (length=259) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRV
EIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRI
HTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRI
THLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRN
LLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQ
EHQADQLAA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6osq The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		G120 D122 E123 Q185 T190 E191 R195 I196 H197 T198
Binding residue
(residue number reindexed from 1)		G24 D26 E27 Q89 T94 E95 R99 I100 H101 T102
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
Biological Process
GO:0006415 translational termination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6osq, PDBe:6osq, PDBj:6osq
PDBsum6osq
PubMed31189921
UniProtP0A7I0|RF1_ECOLI Peptide chain release factor RF1 (Gene Name=prfA)

[Back to BioLiP]