Structure of PDB 6os6 Chain A Binding Site BS03

Receptor Information
>6os6 Chain A (length=362) Species: 391037 (Salinispora arenicola CNS-205) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TEELTTVRDACARTLENTARTLHLGASGTEFVAAFRAMTDHWGAARPHDL
PLSDVSPDGSPVEYAVDLGGLAPALQFAMEPLTAGVPARDPLAARAIMPL
LAGRYGADATRWSALADRLLPDDAHGPHVSMYGAEVRAGAPIRFKAWFYL
NVTGPDGAFNLLYSALERMGTTHLWPVVQAHVHRAGEDVPFLLSLDLSDD
PAARVKVYFRHFAADVEEVAAVLKAYPGFEPGEVRAFCKVMMGGRRRFSD
QPAVTCVSLLDAQTFDRTAATLYVPLWTYAEHDGEVRQRVHRTLAAWPEA
LYRYDSVLAGIAHRGLDAGTGIHNYISWQPGRTRPRMKVYLSPEMHDVTP
PPLGVSQQHHLS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6os6 Chain A Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6os6 Structural Basis of Tryptophan Reverse N-Prenylation Catalyzed by CymD.
Resolution1.33 Å
Binding residue
(original residue number in PDB)		H49 D50
Binding residue
(residue number reindexed from 1)		H48 D49
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0046872 metal ion binding
Biological Process
GO:0009820 alkaloid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6os6, PDBe:6os6, PDBj:6os6
PDBsum6os6
PubMed31251043
UniProtA8M6W6

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