Structure of PDB 6oq7 Chain A Binding Site BS03

Receptor Information
>6oq7 Chain A (length=541) Species: 1496 (Clostridioides difficile) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVEKYLKLKD
INSLTDTYIDTYKKSGRNKALKKFKEYLVIEILELKNSNLTPVEKNLHFI
WIGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIIESASN
DTLESFRENLNDPEFNHTAFFRKRMQIIYDKQQNFINYYKAQKEENPDLI
IDDIVKTYLSNEYSKDIDELNAYIEESLNKVTENSGNDVRNFEEFKTGEV
FNLYEQELVERWNLAGASDILRVAILKNIGGVYLDVDMLPGIHPDLFKDI
NKPDSVKTAVDWEEMQLEAIMKHKEYIPEYTSKHFDTLDEEVQSSFESVL
ASKSDKSEIFLPLGDIEVSPLEVKIAFAKGSIINQALISAKDSYCSDLLI
KQIQNRYKILNDTLGPIISQGNDFNTTMNNFGESLGAIANEENISFIAKI
GSYLRVGFYPEANTTITLSGPTIYAGAYKDLLTFKEMSIDTSILSSELRN
FEFPKVNISQATEQEKNSLWQFNEERAKIQFEEYKKNYFEG
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain6oq7 Chain A Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6oq7 Structure of the full-length Clostridium difficile toxin B.
Resolution2.39 Å
Binding residue
(original residue number in PDB)		D288 E516
Binding residue
(residue number reindexed from 1)		D287 E515
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.-
3.4.22.-
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:6oq7, PDBe:6oq7, PDBj:6oq7
PDBsum6oq7
PubMed31308519
UniProtQ9EXR0|TCDB2_CLODI Toxin B (Gene Name=tcdB)

[Back to BioLiP]