Structure of PDB 6nxj Chain A Binding Site BS03

Receptor Information

>6nxj Chain A (length=307) Species: 666 (Vibrio cholerae)

AEQVHLSGPTMGTTYNIKYIQQPGIADSKTLQTEIDRLLEEVNDQMSTYR
KDSELSRFNQHTSSEPFAVSTQTLTVVKEAIRLNGLTEGALDVTVGPLVN
LWGFGPEARPDVVPTDEELNARRAITGIEHLTIEGNTLSKDIPELYVDLS
TIAKGWGVDVVADYLQSQGIENYMVEIGGEIRLKGLNRDGVPWRIAIEKP
SVQEIIEPGDYAIATSGDYRNYFEQDGVRYSGIIDPTTGRPINNRVVSVT
VLDKSCMTADGLATGLMVMGEERGMAVAEANQIPVLMIVKTDDGFKEYAS
SSFKPFL

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 6nxj Chain A Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6nxj Conserved residue His-257 ofVibrio choleraeflavin transferase ApbE plays a critical role in substrate binding and catalysis.
• Resolution: 1.92 Å
• Binding residue (original residue number in PDB): E200 D285
• Binding residue (residue number reindexed from 1): E180 D260
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.7.1.180: FAD:protein FMN transferase.

Gene Ontology

Molecular Function

• GO:0016740 transferase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0017013 protein flavinylation

Cellular Component

• GO:0005886 plasma membrane

External links

• PDB: RCSB:6nxj, PDBe:6nxj, PDBj:6nxj
• PDBsum: 6nxj
• PubMed: 31350338
• UniProt: A5F5Y3|APBE_VIBC3 FAD:protein FMN transferase (Gene Name=apbE)