Structure of PDB 6m0v Chain A Binding Site BS03

Receptor Information
>6m0v Chain A (length=1030) Species: 322159 (Streptococcus thermophilus LMD-9) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGSDLVLGLDIGIGSVGVGILNKVTGEIIHKNSRIFPAAQAENNLVRRTN
RQGRRLARRKKHRRVRLNRLFEESGLITDFTKISINLNPYQLRVKGLTDE
LSNEELFIALKNMVKHRGISYKTPGQIQLERYQTYGQLRGDFTVEKDGKK
HRLINVFPTSAYRSEALRILQTQQEFNPQITDEFINRYLEILTGKRKYYH
GPGNEKSRTDYGRYRTSGETLDNIFGILIGKCTFYPDEFRAAKASYTAQE
FNLLNDLNNLTVPTETKKLSKEQKNQIINYVKNEKAMGPAKLFKYIAKLL
DVADIKGYRIDKSGKAEIHTFEAYRKMKTLETLDIEQMDRETLDKLAYVL
TLNTEREGIQEALEHEFADGSFSQKQVDELVQFRKANSSIFGKGWHNFSV
KLMMELIPELYETSEEQMTILTRLGYIDEKLLTEEIYNPVVAKSVRQAIK
IVNAAIKEYGDFDNIVIEMARETNEDDEKKAIQKIQKANKDEKDAAMLKA
ANQYNGKAELPHSVFHGHKQLATKIRLWHQQGERCLYTGKTISIHDLINN
SNQFEVDAILPLSITFDDSLANKVLVYATANQEKGQRTPYQALDSMDDAW
SFRELKAFVRESKTLSNKKKEYLLTEEDISKFDVIERNLVDTRYASRVVL
NALQEHFRAHKIDTKVSVVRGQFTSQLRRHWGIEKTRDTYHHHAVDALII
AASSQLNLYQHFVDTLKSKEFEDSILFSYQVDSKFNRKISDATIYATRQA
KVGKDKADETYVLGKIKDIYTQDGYDAFMKIYKKDKSKFLMYRHDPQTFE
KVIEPILENYPNKVPCNPFLKYKEEHGYIRKYSKKGNGPEIKSLKYYDSK
LGNHIDITPKDSNNKVVLQSVSPWRADVYFNKTTGKYEILGLKYADLQFE
KGTGTYKISQEKYNDIKKKEGVDSDSEFKFTLYKNDLLLVKDTETKEQQL
FRFLSRTMPKQKHYVELKPYDKQKFEGGEALIKVLGNVANSGQCKKGLGK
SNISIYKVRTDVLGNQHIIKNEGDKPKLDF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6m0v Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Resolution3.0 Å
Binding residue
(original residue number in PDB)		F673 K867 K941 G943 N944 S961 V962 P964 K984 M1049 Q1084 K1086
Binding residue
(residue number reindexed from 1)		F632 K784 K850 G852 N853 S870 V871 P873 K893 M958 Q993 K995
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6m0v, PDBe:6m0v, PDBj:6m0v
PDBsum6m0v
PubMed
UniProtQ03LF7|CAS9A_STRTD CRISPR-associated endonuclease Cas9 1 (Gene Name=cas9-1)

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