Structure of PDB 6lt4 Chain A Binding Site BS03

Receptor Information
>6lt4 Chain A (length=623) Species: 373153 (Streptococcus pneumoniae D39) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LAKLGRNLTAEAREGKLDPVIGRNKEIQEASEILSRRTKNNPVLVGDAGV
GKTAVVEGLAQAIVNGDVPAAIKNKEIVSIDISGLEAGTQYRGSFEENVQ
NLVNEVKEAGNIILFFDAIHQILGAGSTGGDSGSKGLADILKPALSRGEL
TVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQ
QHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVT
DVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMK
VTASVNDVAESVERMTGIPVSQMGASDIERLKDMAHRLQDKVIGQDKAVE
VVARAICRNRAGFDEGNRPIGNFLFVGSTGVGKTELAKQLALDMFGTQDA
IIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLD
AIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATSNAGFGYEAN
LTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAE
VNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTD
FHLDHLDAKHLEADMEDGVLVIR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6lt4 Chain A Residue 804 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6lt4 ClpL is a functionally active tetradecameric AAA+ chaperone, distinct from hexameric/dodecameric ones.
Resolution4.5 Å
Binding residue
(original residue number in PDB)		K458 T459
Binding residue
(residue number reindexed from 1)		K383 T384
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008233 peptidase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006508 proteolysis
GO:0034605 cellular response to heat
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6lt4, PDBe:6lt4, PDBj:6lt4
PDBsum6lt4
PubMed32910525
UniProtA0A0H2ZMB9

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