Structure of PDB 6ki3 Chain A Binding Site BS03

Receptor Information
>6ki3 Chain A (length=298) Species: 561443 (African swine fever virus tick/South Africa/Pretoriuskop Pr4/1996) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGMFGAFVSHRLWSDSGCTTTCITNSIANYVAFGEQIGFPFKSAQVFIAG
PRKAVINIQEDDKVELLKMIVKHNLWVVAHGTYLDVPWSRRSAFVTHFIQ
QELLICKEVGIKGLVLHLGAVEPELIVEGLKKIKPVEGVVIYLETPHNKH
HTYKYSTMEQIKELFLRIRNTRLKQIGLCIDTAHIWSSGVNISSYNDAGQ
WLRSLENIHSVIPPSHIMFHLNDAATECGSGIDRHASLFEGMIWKSYSHK
IKQSGLYCFVEYITRHQCPAILERNLGSSMQLQTALTAEFTTLKSLLK
Ligand information
Receptor-Ligand Complex Structure
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PDB6ki3 A unique DNA-binding mode of African swine fever virus AP endonuclease.
Resolution2.354 Å
Binding residue
(original residue number in PDB)		S14 R50 Y81 L82 V84 N146 K147 H148 H149
Binding residue
(residue number reindexed from 1)		S16 R52 Y83 L84 V86 N148 K149 H150 H151
Enzymatic activity
Enzyme Commision number 3.1.21.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0008081 phosphoric diester hydrolase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair
Cellular Component
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ki3, PDBe:6ki3, PDBj:6ki3
PDBsum6ki3
PubMed32194979
UniProtP0C9C6|APE_ASFP4 Probable AP endonuclease (Gene Name=Pret-146)

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