Structure of PDB 6jtg Chain A Binding Site BS03

Receptor Information
>6jtg Chain A (length=330) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQAR
IFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHE
IELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAP
DTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT
IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESI
EAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ
QADSFKATRFNLEVREIQEKLDAFIEALHQ
Ligand information
Ligand IDBEF
InChIInChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
InChIKeyOGIAHMCCNXDTIE-UHFFFAOYSA-K
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[Be-](F)(F)F
ACDLabs 10.04
CACTVS 3.341		F[Be-](F)F
FormulaBe F3
NameBERYLLIUM TRIFLUORIDE ION
ChEMBL
DrugBank
ZINC
PDB chain6jtg Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6jtg Structural insights into G domain dimerization and pathogenic mutation of OPA1.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		S36 K39 M60 T61 G139
Binding residue
(residue number reindexed from 1)		S36 K39 M60 T61 G139
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.5: dynamin GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:6jtg, PDBe:6jtg, PDBj:6jtg
PDBsum6jtg
PubMed32379273
UniProtO60313|OPA1_HUMAN Dynamin-like GTPase OPA1, mitochondrial (Gene Name=OPA1)

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