Structure of PDB 6je4 Chain A Binding Site BS03 |
| >6je4 Chain A (length=1049) Species: 604162 (Neisseria meningitidis 8013)
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SINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDS
LAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLP
NTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNELGALLKGVAG
NAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELIL
LFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAE
PKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSK
LTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEG
LKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKH
ISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDNTEEKIYLPPIPA
DEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEI
EKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYS
GKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTP
YEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLND
TRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAEN
DRHHALDAVVVACSTVAMQQKITRFVRYKEMNAHQKTHFPQPWEFFAQEV
MIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRA
PNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPK
LYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGV
WVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGK
DEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIR
IHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR |
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| PDB | 6je4 Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. |
| Resolution | 3.069 Å |
Binding residue
(original residue number in PDB) | S57 L58 A59 R62 R63 R66 R69 R70 L71 R73 R74 H77 R78 R81 R83 R84 R88 N108 P110 W111 H133 K136 R138 G139 G190 H191 I192 R193 N194 Q195 R196 Q242 R243 A245 T259 V421 Q422 Y441 P466 R473 R479 R485 K486 R493 R665 T670 R675 P834 R836 K837 M838 S839 G840 Q841 G842 H843 V847 S849 K851 R861 N877 R880 E881 K883 D911 T917 Q919 K921 A922 R924 R936 N939 S966 W967 A970 K971 E1065 R1071 C1073 P1080 V1081 |
Binding residue
(residue number reindexed from 1) | S50 L51 A52 R55 R56 R59 R62 R63 L64 R66 R67 H70 R71 R74 R76 R77 R81 N101 P103 W104 H126 K129 R131 G132 G176 H177 I178 R179 N180 Q181 R182 Q228 R229 A231 T245 V407 Q408 Y427 P447 R454 R460 R466 K467 R474 R646 T651 R656 P801 R803 K804 M805 S806 G807 Q808 G809 H810 V814 S816 K818 R828 N844 R847 E848 K850 D878 T884 Q886 K888 A889 R891 R903 N906 S933 W934 A937 K938 E1032 R1038 C1040 P1047 V1048 |
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