Structure of PDB 6iml Chain A Binding Site BS03

Receptor Information
>6iml Chain A (length=403) Species: 10497 (African swine fever virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLNQFPGQYSNNIFCFPPIESETKSGKKASWIICVQVVQHNTIIPITDEM
FSTDVKDAVAEIFTKFFVEEGAVRISKMTRVTEGKNLGKKNATTVVHQAF
KDALSKYNRHARQKRGMIPPMLVKYFNIIPKTFFEEETDPIVQRKRNGVR
AVACQQGDGCILLYSRTEKEFLGLDNIKKELKQLYLFIDVRVYLDGELYL
HRKPLQWIAGQANAKTDSSELHFYVFDCFWSDQLQMPSNKRQQLLTNIFK
QKEDLTFIHQVENFSVKNVDEALRLKAQFIKEGYEGAIVRNANGPYEPGY
NNYHSAHLAKLKPLLDAEFILVDYTQGKKGKDLGAILWVCELPNKKRFVV
TPKHLTYADRYALFQKLTPALFKKHLYGKELTVEYAELSPKTGIPLQARA
VGF
Ligand information
Receptor-Ligand Complex Structure
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PDB6iml Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		K27 R74 K359 T362 Y363 Q403 R405
Binding residue
(residue number reindexed from 1)		K27 R74 K353 T356 Y357 Q397 R399
Enzymatic activity
Enzyme Commision number 6.5.1.1: DNA ligase (ATP).
Gene Ontology
Molecular Function
GO:0003909 DNA ligase activity
GO:0003910 DNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0051301 cell division
Cellular Component
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6iml, PDBe:6iml, PDBj:6iml
PDBsum6iml
PubMed30674878
UniProtP35970|DNLI_ASFB7 DNA ligase (Gene Name=LIG)

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